This talk will present the example of a 32-year-old gravida 6 para 3 in the second trimester; her pregnancies have been notably complicated by high-titer alloimmunization (especially against D antigen). Mechanism and pathophysiology will be discussed, along with treatments (including IV immunoglobulins and intrauterine transfusion) that are available for this condition.
Learning Objectives:
- Comprehend the etiology and pathophysiology of HDFN (hemolytic disease of the fetus and newborn).
- Grasp the means of working up and monitoring HDFN during pregnancy.
- Commit to memory the modalities of treatment for HDFN, including new medication.
